Prussian blue and its analogues as artificial enzymes and prospects for their application

In recent years, Prussian blue nanoparticles (PB-NPs) and theire analogues, that exhibit an increased catalytic activity, have attracted considerable attention in nanotechnology. Such are regarded as alternative to natural enzymes intensively used biosensorics, diagnostics experimental biomedicine. Recently, it has been shown their analogs, also referred “nanozymes”, can be active oxygen scavengers antibacterial or anti-inflammatory drugs due polyenzymatic activities, namely oxidase, peroxidase, superoxide dismutase. Their excellent biocompatibility biodegradability mean they ideal for vivo use. highly efficient electron transporters engage oxidation reduction which makes them promising mediators catalysts of reactions. They show great promise nanodrug carriers biological detection sensors large specific surface area, unique chemical characteristics, variable qualities, which, more importantly, significantly increase therapeutic effect. nanoparticles, diagnostic tools, achieved significant success nanomedicine. This review is devoted the methods synthesis study structure, properties role creation analytical significance